Updated 2026-07-31
Anomalous aortic origin of a coronary arteryAAOCA / AAORCA
If you or someone in your family has just been given this diagnosis, this library organises the published research around the questions you are most likely to ask.
This site organises published research to help you talk with your clinician. It does not replace medical diagnosis or advice.
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What this condition is
The heart needs its own blood supply, delivered by the two coronary arteries. They arise from the root of the aorta, one on each side, each from its own fixed position.
Anomalous aortic origin of a coronary artery (AAOCA) means one of those arteries begins in the wrong place — for example, an artery that should arise on the left instead arises on the right. If that vessel then runs between the aorta and the pulmonary artery, the chance of it being compressed increases. This is a difference in anatomy present from birth, not an illness acquired later, and it is not contagious.
Many people never have symptoms and are found incidentally during testing done for another reason. Others experience chest pain, breathlessness on exertion, or fainting, and in a small number of cases the condition is linked to cardiac events during intense exercise. Risk depends on the specific anatomy, needs imaging to assess, and varies considerably between individuals.
The questions below are the ones families ask most often. Under each are the relevant records — they show what the research currently reports, but they cannot substitute for your clinician's assessment of your own situation.
Browse by question
What you may want to ask
Each question opens with a short note on how far the evidence goes and where it remains unsettled.
What is this condition
Where the coronary arteries arise, and why position matters
12 recordsHow serious is it
Risk stratification, sudden death, long-term follow-up
25 recordsWhich tests are used
What CT, MRI, echocardiography, and stress testing can show
16 recordsCan sport continue
Activity restriction, return to training, competitive participation
5 recordsIs surgery needed
Indications, operative techniques, post-operative outcomes
27 recordsWhat clinicians rely on
Consensus statements and clinical guidelines
8 recordsAll records
Search the collection
Titles remain in their publication language.
Adults with anomalous aortic origin of a coronary artery: impact of invasive functional testing on clinical decision making - insights from the MuSCAT registry
European Heart Journal - Imaging Methods and Practice
Bibliographic record only — the full text must be obtained from the publisher.
Anomalous Aortic Origin of the Right Coronary Artery in Adults: Surgical Reimplantation With Intermediate-Term Results
World Journal for Pediatric and Congenital Heart Surgery
Bibliographic record only — the full text must be obtained from the publisher.
Clinical characteristics and outcomes of the anomalous aortic origin of a coronary artery: a nationwide pediatric survey in Japan
Heart and Vessels
Bibliographic record only — the full text must be obtained from the publisher.
Fluid dynamics-informed CCTA-derived geometric parameters in right coronary artery anomalies predict abnormal invasive Adenosine-FFR and Dobutamine-FFR
Complete manuscript; journal/DOI not stated in local file
Histological assessment of the intramural segment in adults with an anomalous aortic origin of a coronary artery with an interarterial course
BMC Cardiovascular Disorders
Prevalence and anatomical variants of anomalous aortic origin of a coronary artery assessed by coronary CT angiography: a single-center study
European Heart Journal - Cardiovascular Imaging (conference abstract)
Bibliographic record only — the full text must be obtained from the publisher.
Proposed Standardized Nomenclature for Anomalous Aortic Origin of a Coronary Artery: An International Multidisciplinary Initiative
JACC: Cardiovascular Imaging
Bibliographic record only — the full text must be obtained from the publisher.
Risk stratification and real-world management of pediatric AAORCA: discordance between anatomical features and clinical symptoms
Frontiers in Cardiovascular Medicine
Single-center clinical analysis of anomalous aortic origin of a coronary artery (AAOCA) in children: a multimodal imaging approach to risk stratification
Journal of Cardiothoracic Surgery
Surgical Outcomes of anomalous aortic origin of coronary arteries: early and mid-term results from a single-center experience
BMC Pediatrics
AI-based detection and classification of anomalous aortic origin of coronary arteries using coronary CT angiography images
Nature Communications
Anomalous Aortic Origin of a Coronary Artery: Results from a Single Surgical Team in Spain
World Journal for Pediatric and Congenital Heart Surgery
Clinical and Prognostic Significance of Anomalous Origin of a Coronary Artery in Adults
Circulation
Bibliographic record only — the full text must be obtained from the publisher.
Clinical Considerations for Competitive Sports Participation for Athletes With Cardiovascular Abnormalities: A Scientific Statement From the American Heart Association and American College of Cardiology
Circulation
Bibliographic record only — the full text must be obtained from the publisher.
Outcomes of 230 Patients Undergoing Surgical Repair of Anomalous Aortic Origin of a Coronary Artery
The Annals of Thoracic Surgery
Bibliographic record only — the full text must be obtained from the publisher.
Right Axillary Thoracotomy for Anomalous Aortic Origin of a Coronary Artery in Children
Congenital Heart Disease
Surgical approach and outcomes in adults with anomalous aortic origin of coronary arteries at a reference center: Outcomes of proximal coronary surgery
JTCVS Open
Bibliographic record only — the full text must be obtained from the publisher.
Surgical treatment of anomalous aortic origin of the coronary artery in paediatric patients: a Chinese single-center experience
BMC Surgery
The Diagnosis and Therapeutic Management of Anomalous Aortic Origin of the Coronary Artery: A Retrospective Study Conducted at a Single Center in China
Reviews in Cardiovascular Medicine
Bibliographic record only — the full text must be obtained from the publisher.
First report from the European registry for anomalous aortic origin of coronary artery (EURO-AAOCA)
Interdisciplinary CardioVascular and Thoracic Surgery
Fluid-structure interaction simulations for the prediction of fractional flow reserve in pediatric patients with anomalous aortic origin of a coronary artery
arXiv preprint
Surgical outcomes in adolescents and adults with anomalous aortic origin of a coronary artery
Frontiers in Cardiovascular Medicine
Anomalous right coronary artery originating from the aorta: a series of nine pediatric cases
BMC Pediatrics
Application of Patient-Specific Computational Fluid Dynamics in Anomalous Aortic Origin of Coronary Artery: A Systematic Review
Journal of Cardiovascular Development and Disease
Bibliographic record only — the full text must be obtained from the publisher.
Clinical analysis of sixty-nine children with anomalous aortic origin of the coronary artery
European Journal of Pediatrics
Clinical presentation and medium-term outcomes of children with anomalous aortic origin of the left coronary artery: high-risk features beyond interarterial course
Circulation: Cardiovascular Interventions
Bibliographic record only — the full text must be obtained from the publisher.
Ischemia in Anomalous Aortic Origin of a Right Coronary Artery: Large Pediatric Cohort Medium-Term Outcomes
Circulation: Cardiovascular Interventions
Bibliographic record only — the full text must be obtained from the publisher.
Management of Adults With Anomalous Aortic Origin of the Coronary Arteries: State-of-the-Art Review
Journal of the American College of Cardiology
Bibliographic record only — the full text must be obtained from the publisher.
Trends in surgical management of anomalous aortic origin of the coronary artery over 2 decades
JTCVS Open
Bibliographic record only — the full text must be obtained from the publisher.
Anomalous Aortic Origin of Right Coronary Artery: Outcomes of Surgical and Nonsurgical Treatment
The Annals of Thoracic Surgery
Bibliographic record only — the full text must be obtained from the publisher.
Congenital Anomalous Origin of Coronary Artery Disease in Children With Syncope: A Case Series
Frontiers in Pediatrics
Coronary artery disease in adults with anomalous aortic origin of a coronary artery
JTCVS Open
Bibliographic record only — the full text must be obtained from the publisher.
Surgery for Anomalous Aortic Origin of a Coronary Artery (AAOCA) in Children and Adolescents: A Meta-Analysis
World Journal for Pediatric and Congenital Heart Surgery
2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease
European Heart Journal
Bibliographic record only — the full text must be obtained from the publisher.
Anomalous Aortic Origin of a Coronary Artery Repair Through an Anterior Minithoracotomy
Innovations
The significance of symptoms before and after surgery for anomalous aortic origin of coronary arteries in adolescents and adults
Interactive CardioVascular and Thoracic Surgery
Bibliographic record only — the full text must be obtained from the publisher.
2020 ESC Guidelines for the management of adult congenital heart disease
European Heart Journal
Bibliographic record only — the full text must be obtained from the publisher.
Anomalous aortic origin of a coronary artery in two children
Asian Cardiovascular & Thoracic Annals
Coronary Computed Tomography Angiography-Derived Fractional Flow Reserve in Patients with Anomalous Origin of the Right Coronary Artery from the Left Coronary Sinus
Korean Journal of Radiology
Exercise-Induced Abnormalities of Regional Myocardial Deformation in Anomalous Aortic Origin of the Right Coronary Artery
World Journal for Pediatric and Congenital Heart Surgery
Outcomes after anomalous aortic origin of a coronary artery repair: A Congenital Heart Surgeons' Society Study
Journal of Thoracic and Cardiovascular Surgery
Bibliographic record only — the full text must be obtained from the publisher.
Recommendations for Multimodality Assessment of Congenital Coronary Anomalies: A Guide from the American Society of Echocardiography
Journal of the American Society of Echocardiography
先天性心脏病外科治疗中国专家共识(十二):先天性冠状动脉异常
中国胸心血管外科临床杂志
2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease
Journal of the American College of Cardiology
Features associated with myocardial ischemia in anomalous aortic origin of a coronary artery: A Congenital Heart Surgeons' Society study
Journal of Thoracic and Cardiovascular Surgery
Perfusion Study Helps in the Management of the Intraseptal Course of an Anomalous Coronary Artery
World Journal for Pediatric and Congenital Heart Surgery
Clinical Strategies of Anomalous Aortic Origin of the Coronary Artery Arising from the Opposite Sinus
中国分子心脏病学杂志
Outcomes of surgical intervention for anomalous aortic origin of a coronary artery: A large contemporary prospective cohort study
Journal of Thoracic and Cardiovascular Surgery
Bibliographic record only — the full text must be obtained from the publisher.
Patients with anomalous aortic origin of the coronary artery remain at risk after surgical repair
Journal of Thoracic and Cardiovascular Surgery
Bibliographic record only — the full text must be obtained from the publisher.
Anomalous Aortic Origin of a Coronary Artery From the Inappropriate Sinus of Valsalva
Journal of the American College of Cardiology
Bibliographic record only — the full text must be obtained from the publisher.
Clinical evaluation of anomalous aortic origin of a coronary artery (AAOCA)
Congenital Heart Disease
Bibliographic record only — the full text must be obtained from the publisher.
Expert consensus guidelines: Anomalous aortic origin of a coronary artery
Journal of Thoracic and Cardiovascular Surgery
Outcome in middle-aged individuals with anomalous origin of the coronary artery from the opposite sinus: a matched cohort study
European Heart Journal
Bibliographic record only — the full text must be obtained from the publisher.
Anomalous Coronary Arteries: Analysis of Clinical Outcome Based Upon Arterial Course and Surgical Intervention in an Adult Population
Academic Radiology
Bibliographic record only — the full text must be obtained from the publisher.
Decision analysis to define the optimal management of athletes with anomalous aortic origin of a coronary artery
Journal of Thoracic and Cardiovascular Surgery
Bibliographic record only — the full text must be obtained from the publisher.
Eligibility and Disqualification Recommendations for Competitive Athletes With Cardiovascular Abnormalities: Task Force 4: Congenital Heart Disease: A Scientific Statement From the American Heart Association and American College of Cardiology
Circulation
Anomalous Aortic Origin of a Coronary Artery: A Report From the Congenital Heart Surgeons Society Registry
World Journal for Pediatric and Congenital Heart Surgery
Bibliographic record only — the full text must be obtained from the publisher.
Surgical repair of anomalous aortic origin of a coronary artery
European Journal of Cardio-Thoracic Surgery
Bibliographic record only — the full text must be obtained from the publisher.
Surgical unroofing of anomalous aortic origin of a coronary artery: a single-center experience
The Annals of Thoracic Surgery
Bibliographic record only — the full text must be obtained from the publisher.
The distribution and prognosis of anomalous coronary arteries identified by cardiovascular magnetic resonance: 15 year experience from two tertiary centres
Journal of Cardiovascular Magnetic Resonance
Anomalous aortic origin of coronary arteries from the opposite sinus: A critical appraisal of risk
BMC Cardiovascular Disorders
Anomalous Aortic Origin of a Coronary Artery: Preoperative Diagnosis and Surgical Planning
World Journal for Pediatric and Congenital Heart Surgery
The registry of anomalous aortic origin of the coronary artery of the Congenital Heart Surgeons' Society
Cardiology in the Young
Bibliographic record only — the full text must be obtained from the publisher.
Curation principles
Traceable, verifiable, honest about access
Pediatric and adult kept apart
Mixed-age studies are assigned once, with the rationale retained in the source index.
Guidance stands on its own
Consensus statements and clinical guidelines remain independently searchable, because they are what clinicians rely on.
Missing full text is stated plainly
Records without full text are marked as such and point to a lawful source. No abstract is ever presented as the paper.